CrossFire® Bed Bug Concentrate
Kills adults, nymphs and eggs, including resistant strains
One 13 fl. oz. bottle plus 115 fl. oz. of water makes a finished gallon and treats up to 1,000 sq. ft. Spray it into the seams, joints and cracks where bed bugs sit out the day, mattresses included, and the treated surfaces keep working for up to four weeks after the spray dries.
Bed Bug Control Built Around Resistance
Most bed bug populations in the United States now survive pyrethroids, the chemical class behind almost every bed bug spray on a hardware store shelf. The EPA names that resistance as a central problem in bed bug control and points to products combining different chemical classes as the way past it.
CrossFire was formulated for exactly that. Two insecticidal modes of action hit separate targets in the insect nervous system, and a synergist strips away the enzyme defence a resistant strain relies on. A bug that shrugs off one route still meets a second it has no answer for.
4.00%
Clothianidin
Group 4A neonicotinoid
Acts on the nicotinic acetylcholine receptor, a target with nothing in common with the one pyrethroids hit. Clothianidin carries most of the residual work, which is what keeps a treated seam dangerous to a bed bug days after the spray dried.
0.40% in the finished spray
0.10%
Metofluthrin
Group 3A pyrethroid
A sodium channel modulator and the fast half of the formula. Independent testing found control from direct contact in under five minutes. Metofluthrin is what makes a bug you spray on the mattress stop moving while you watch.
0.01% in the finished spray
10.00%
Piperonyl butoxide
Synergist, not an insecticide
PBO kills nothing by itself. It blocks the P450 enzymes a bed bug uses to break an insecticide down before it reaches its target, which is one of the main ways a resistant strain walks away from a spray that should have worked.
1.00% in the finished spray
CrossFire is a suspo-emulsion, a format that holds ingredients with different physical properties together in one water-dilutable liquid. That is why the bottle needs a shake before you measure and the tank needs another one partway through a long job.
Kills Adults, Nymphs and Bed Bug Eggs
Every bed bug life stage is on the label. Direct contact kills adults and nymphs, and the formula kills eggs on contact and stops treated eggs from hatching. Pyrethroid-resistant and susceptible strains are both named.
The eggs are the reason this matters. Bed bugs you can see at 2 a.m. are a small share of what is in the room, and the eggs sit glued into mattress seams, screw holes and the gap behind a headboard. A product that only reaches moving insects hands the infestation a fresh generation about ten days later, which is how a treatment that looked like it worked falls apart in week two.
Vacuum before you spray. It removes debris, shed skins and some of the insects, and it opens up harborages the spray then has to get into. Once you are spraying, hit visible bugs and eggs directly wherever you can reach them.
Fast Knockdown, Then Four Weeks of Residual
The label gives residual control for up to four weeks after application. Treated surfaces stay active once the spray dries, so a bed bug that stayed hidden through the entire treatment can still pick up a lethal dose later, crossing a seam you sprayed on day one.
That is the part no single pass of an aerosol can do. Contact kill only counts against insects you actually find, and in a real bedroom you never find all of them.
Surface type, cleaning and the size of the infestation all change how the residue behaves in a particular house. The label sets no minimum interval between treatments, so a second pass is a judgment call based on what the room is doing rather than a date on a calendar.
Under 5 min
Direct contact
Control from direct contact in under five minutes in independent testing. This is the metofluthrin half of the formula doing its job on a bug you can see.
4 weeks
Labeled residual
Treated harborages stay lethal after the spray dries, which covers the insects that were tucked somewhere you could not reach on the day.
Non-repellent
No warning to move
Bed bugs are not driven away from treated surfaces, so a repellent effect does not scatter the population into the next room ahead of the residual.
What Buyers Say
This product worked amazingly well for my infestation. Last time I had these nasty little vampires, I paid $1100 for a professional exterminator. Months later, they were back. I couldn’t afford another professi...
Pamela Hight
WARNING: THIS IS A LONG RANT. I moved out about a year ago and made the mistake of buying a nice used couch from the Facebook market— in which I am truly scarred. WORSE. MISTAKE. EVER! After a few months of be...
Pn
If you are tired of wasting your money on the stuff that doesn't work, you really need to get this. It really actually kills them and we have not had any return. I wish I would have gotten this stuff first.
Diana Hoskins
Does work , only thing that does we got rid of them after 2 sprays and using the under bed leg traps took about 3 months but they have been gone for a year now no more signs at all we did buy one more bottle of...
Sandy R
Best to use when needing something that works to get rid of the problem. No smell, no residue. Works fast and easy to use.
Devon Kelley
If you are questioning if this works, the answer is yes. 100% yes. It's not gonna work if you just spray and be on your way. No. Still do the full bedbug protocol. Dry everything you can on high heat for at lea...
Katrina
How Much CrossFire per Gallon of Water
Pour the entire 13 fl. oz. bottle into 115 fl. oz. of water. That is one finished gallon at 1.42% total actives, and it covers up to 1,000 sq. ft. The 13 oz bottle is deliberately a single dose, so when a gallon is what you need there is nothing to measure and nothing to get wrong.
| Finished spray | Water | CrossFire | Treats |
|---|---|---|---|
| 16 fl. oz. | 14.4 fl. oz. | 1.6 fl. oz. | 125 sq. ft. |
| 1 quart | 28.8 fl. oz. | 3.2 fl. oz. | 250 sq. ft. |
| 0.5 gallon | 57.5 fl. oz. | 6.5 fl. oz. | 500 sq. ft. |
| 1 gallon | 115 fl. oz. | 13 fl. oz. | 1,000 sq. ft. |
| 1.5 gallons | 172.5 fl. oz. | 19.5 fl. oz. | 1,500 sq. ft. |
Mixing order matters
Shake the bottle first
Invert the container several times before you measure anything. CrossFire is a suspo-emulsion, so the ingredients separate on a shelf and a poured dose off the top is not the dose on the label.
Half the water goes in first
Fill the sprayer with roughly half the water you need. Water temperature and pH make no difference to the formulation, so tap water straight from the sink is fine.
Add the CrossFire
Thirteen fluid ounces for a full finished gallon. From a 13 oz bottle that is the whole bottle, so nothing gets measured.
Top up, close, shake
Agitate the tank, then add the remaining water slowly until you hit the finished volume. Close it and shake thoroughly before the first pull of the trigger.
Water and nothing else
Water is the only diluent. Temperature and pH do not affect the formulation, so there is no reason to warm it, filter it or treat it first.
Shake it again
Agitate the tank if you stop partway through, and again before you restart. Diluted CrossFire may be stored overnight, though a batch used inside 24 hours is the practical target.
More is not stronger
Thirteen ounces per gallon is the rate the label sets. Doubling it does not shorten the job, and using a registered pesticide above its labeled rate breaks federal law.
Where to Spray CrossFire for Bed Bugs
Bed bugs stay near a sleeping host, so the bed and the three feet around it earn most of the result from a treatment. A growing population then spreads outward, which is why an inspection that stops at the mattress usually misses part of the infestation.
Apply as a pinstream, coarse spray or low-pressure spray to indoor non-food areas. A paintbrush works better than a spray tip on walls, baseboards, floorboards and the backs of wall hangings, and it puts the product where you want it instead of on the air.
On and around the bed
Mattress seams, folds, tufts and edges. Box spring, bed frame, headboard and the wall directly behind it. This is where the highest return on a treatment sits, because bed bugs stay close to a sleeping host until a population outgrows the space.
Room edges
Baseboards, floorboards, millwork and the carpet perimeter, plus beneath floor coverings where the edge lifts. These are travel routes as much as harborages.
Furniture and fittings
Joints and seams of upholstered furniture, door and window frames, closets, window treatments and the backs of wall hangings. A paintbrush reaches most of these more accurately than a spray tip.
Things that cannot be washed
Luggage, shoes, backpacks and similar items that will never survive a hot wash cycle. Treat them rather than throwing them out or letting them sit untreated in a closet.
Pet areas
Pet beds, bedding, sleeping areas, floors and furnishings, with the animal out of the room and back only once everything is dry. Never spray an animal.
Anywhere activity shows
Dark specks along a seam, shed skins, live insects. Spray bed bugs and eggs directly whenever you can get at them, since direct contact is the fastest kill this product delivers.
Direct mattress application is on the label
Treat mattress seams, folds, tufts and edges, then the box spring and bed frame. On porous surfaces spray until the surface is thoroughly damp and stop there. Runoff and dripping are overapplication, not thoroughness.
Bed linens get handled a different way. Strip the sheets, pillowcases and blankets, seal them in a bag before you carry them through the house, then wash and dry them on high heat. Remake the bed with clean linens only after the mattress has dried completely.
What CrossFire is not for
- •Not a space spray and not a fogger. Not for broadcast application across a room.
- •Never on people or animals, and never sprayed directly at a pet.
- •No plants, no crops.
- •Not in commercial food or feed processing, preparation, storage or serving areas. At home, cover or remove exposed food and wash any food surfaces or utensils left uncovered.
- •Nothing in, on or around electrical equipment. That one is a shock hazard, not a residue question.
- •Do not treat a room with people in it, and keep everyone out until every treated surface is dry.
- •Do not wet anything to the point of runoff or dripping.
Handling, PPE and Re-Entry
What to wear
Long-sleeved shirt, long pants, shoes and socks. Wash with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Keep contaminated work clothing out of the household laundry, and discard anything drenched in concentrate rather than washing it.
Empty the room, then wait for dry
Nobody is in the area during application. Adults, children and pets return only once treated surfaces have dried. Birds come out of the room and fish aquariums get covered before you start.
No signal word is not the same as no precautions
CrossFire carries no EPA-required signal word, so the front panel has no CAUTION, WARNING or DANGER on it. That is a toxicity classification. It remains a registered insecticide, and federal law makes the label directions binding.
Keep it away from electrical equipment
Do not apply in, on or around electrical equipment. Outlets, switch plates and the back of a wall-mounted TV all count. Bed bugs do use outlet boxes, and that is one harborage this product is not the tool for.
First aid
In the eyes: hold the eye open and rinse slowly with water for 15 to 20 minutes, taking contact lenses out after the first five minutes and then continuing to rinse. On skin or clothing: take the clothing off and rinse skin for 15 to 20 minutes. Call a poison control center for treatment advice. For health concerns, medical emergencies or pesticide incidents call 1-888-740-8712 with the container in your hand.
The empty container
Non-refillable. Do not reuse or refill it. Triple rinse instead: fill it a quarter full, recap, shake for 10 seconds, pour the rinsate into the spray tank, drain 10 seconds after it starts to drip, then repeat twice more. Recycle it if a program takes it, or puncture it and dispose of it as your state or local rules allow.
Storage and Shelf Life
Where it lives between jobs
Original container, cap tight, somewhere cool and dry away from excess heat. Keep it from freezing, and store it where it cannot contaminate water, food or feed.
Three years or more
That is the shelf life under ideal storage conditions, so a bottle bought for one infestation is still usable if the next one arrives two winters later.
If it froze anyway
Let it thaw, then shake it thoroughly before use. A garage shelf in January is the usual way this happens.
What it smells like
A slight sweet smell, and it is not listed as flammable or combustible. Several buyers describe the scent as light and pleasant, which is not something most bed bug products get said about them.
Diluted spray
Mix the amount the job needs. Diluted CrossFire may be stored overnight, though using a batch within 24 hours is the practical target. A tank left standing gets shaken again before you carry on.
No fixed retreatment interval
The label sets no minimum gap between treatments. Base a second pass on what the room is actually doing, checking the harborages that were active the first time.
13 oz and 130 oz
13 fl. oz.
One full dose
Empty the bottle into 115 fl. oz. of water and you have one finished gallon for up to 1,000 sq. ft. Nothing gets measured, which removes the step people most often get wrong. This is the size for one bedroom, one apartment or one job.
Check price130 fl. oz.
Ten finished gallons
Enough concentrate for up to 10,000 sq. ft. at the labeled rate. The measuring chamber is marked at 13, 6.5 and 3.2 fl. oz., the three doses that come up most often, and the handle is positioned so a pour into the chamber does not end up on the floor.
Check priceCrossFire Concentrate or CrossFire Aerosol
CrossFire exists as a water-dilutable concentrate and as a ready-to-use 17 oz aerosol. Both are indoor bed bug products, both handle pyrethroid-resistant strains and every labeled life stage, and both are cleared for direct mattress application.
Searches for a CrossFire bug spray or a CrossFire spray land on one of those two. The concentrate is never sold ready to use, and the aerosol is never diluted. Picking the wrong one usually means either buying ten cans for a job that needed a gallon, or buying a sprayer for a job that needed one can.
| Concentrate | Aerosol | |
|---|---|---|
| Ready to use | No, dilute with water | Yes |
| Sizes | 13 oz and 130 oz | 17 oz can |
| Coverage | Up to 1,000 sq. ft. per 13 oz | Targeted spots and cracks |
| Applied with | Handheld or backpack sprayer, or a paintbrush | Straight from the can |
| Best for | Whole rooms and heavy harborage treatment | Small jobs and touch-ups |
| Resistant strains | Yes | Yes |
| Mattress application | Yes, per label | Yes, per label |
For a bedroom, an apartment or anything that needs real surface coverage, the concentrate produces far more finished spray for the money. The aerosol earns its place on a small targeted job, where getting a sprayer out and cleaning it afterwards is more work than the treatment itself.
CrossFire Is an MGK Product
MGK started grinding spices in Minneapolis in 1902 and moved into botanical insecticides soon after, producing pyrethrum by 1915. A broader portfolio of botanical and conventional insect control chemistry followed, and Sumitomo Chemical took an ownership position in 1989.
CrossFire arrived in 2016 as a direct answer to bed bug infestations that had stopped responding to pyrethroids. It is not a general household insecticide relabeled for another pest. Mattress application is written into the label, eggs are on the label, resistant strains are named by category, and the dilution rate and application methods are built around indoor bed bug harborages rather than a perimeter treatment.
The container is HDPE and fully recyclable, the formulation runs very low on volatile organic compounds, and the shipping cartons and paper labels come from sustainably managed forests.
CrossFire is manufactured for MGK under EPA Reg. No. 1021-2776 and EPA Est. No. 1021-MN-2, covered by U.S. Patent 8,889,721. CrossFire is a registered trademark of Sumitomo Chemical Co., Ltd.
CrossFire at a Glance
| Specification | CrossFire Bed Bug Concentrate |
|---|---|
| Primary pest | Bed bugs |
| Life stages controlled | Eggs, nymphs and adults |
| Resistant strains | Pyrethroid-resistant and susceptible |
| Form | Suspo-emulsion concentrate |
| Clothianidin | 4.00% |
| Metofluthrin | 0.10% |
| Piperonyl butoxide | 10.00% |
| Finished concentration | 1.42% total actives |
| Dilution | 13 fl. oz. concentrate + 115 fl. oz. water |
| Coverage | 1 finished gallon per 1,000 sq. ft. |
| Use | Indoor only |
| Mattress application | Yes, per label directions |
| Application methods | Spot, crack and crevice, carpet perimeter, direct spray |
| Equipment | Handheld sprayer, backpack sprayer or paintbrush |
| Labeled residual | Up to 4 weeks |
| Retreatment interval | None specified |
| Signal word | None |
| Shelf life | 3 years or more in ideal storage |
| Package sizes | 13 fl. oz. and 130 fl. oz. |
| EPA Reg. No. | 1021-2776 |
| EPA Est. No. | 1021-MN-2 |
| U.S. Patent | 8,889,721 |
Frequently Asked Questions
CrossFire Bed Bug Concentrate is an indoor insecticide developed specifically for bed bug control. The formula kills adults, nymphs and eggs, including pyrethroid-resistant strains. It combines clothianidin and metofluthrin with piperonyl butoxide to provide fast knockdown plus residual activity after the treated surface dries.
Use 13 fl. oz. of CrossFire Concentrate with 115 fl. oz. of water to make one gallon of finished spray. One finished gallon treats up to 1,000 sq. ft. at the labeled application rate. Smaller batches can be mixed using the same dilution ratio.
The CrossFire label provides residual control for up to four weeks. MGK also cites third-party laboratory testing that found more than 90% control on certain treated surfaces after much longer aging periods. Those laboratory results do not replace the four-week labeled residual or guarantee identical performance in every building.
Yes. CrossFire is labeled to kill bed bugs at all life stages, including eggs. Direct contact with eggs helps prevent hatching, which is important because eggs can remain hidden deep inside mattress seams, furniture joints and narrow cracks.
Yes. CrossFire was specifically formulated to control pyrethroid-resistant as well as susceptible bed bug strains. Clothianidin provides a different insecticidal mode of action from metofluthrin, and piperonyl butoxide helps counter certain metabolic resistance mechanisms.
Yes, when used according to the product label. CrossFire can be applied to mattress seams, folds, tufts and edges where bed bugs hide. Apply enough finished spray to dampen the surface without soaking it, then allow the mattress to dry completely before putting clean bedding back in place. Do not spray sheets, pillowcases, blankets or other washable bed linens. Those should be removed and laundered separately.
Focus treatment on the places bed bugs use as harborages or travel routes. Common areas include mattress seams, box springs, bed frames, headboards, baseboards, furniture joints, carpet edges and cracks around walls or flooring. CrossFire is intended for targeted indoor application rather than indiscriminate spraying across every exposed surface in a room.
People and pets should stay out of the treatment area during application and should not return until treated surfaces have dried. CrossFire must never be applied directly to people or animals. Fish aquariums should be covered and birds removed from the treatment area before spraying. Always follow the current product label for application, protective equipment and re-entry instructions.
CrossFire is labeled as non-staining on water-safe fabrics and surfaces. Dark materials can sometimes show a light visible residue after drying, similar to residue from a wettable powder. It can usually be removed with a damp cloth. Test a small inconspicuous area before treating delicate fabrics or finishes.
CrossFire Concentrate is diluted with water and applied using a sprayer, making it suitable for treating larger areas and multiple harborages. A 13 oz bottle produces one gallon of finished solution. CrossFire Aerosol comes ready to use in a 17 oz can and is more convenient for smaller, targeted applications where mixing a full sprayer is unnecessary. Both products are designed specifically for bed bugs and can control pyrethroid-resistant strains.
The label provides residual control for up to four weeks and sets no minimum interval between treatments, so retreatment should be based on continued bed bug activity and label directions rather than an automatic calendar schedule. Inspect treated rooms carefully after the initial application and pay particular attention to previously active harborages. Persistent infestations may require additional treatment because bed bugs can remain hidden in untreated cracks, adjacent rooms or belongings.
The label permits it. CrossFire may be tank mixed with other insecticides, and the conditions come with it: run a small jar compatibility test using the correct proportions of each product and water before mixing a full tank, follow the use directions and precautions of both labels, and apply under the more restrictive of the two sets of limitations. No labeled application rate may be exceeded, and CrossFire cannot be mixed with any product whose label prohibits tank mixing. A tank mix is rarely necessary in a bed bug job, since CrossFire already carries two insecticidal modes of action plus a synergist. Raising the concentration is never an option, mixed or not.
CrossFire is developed and marketed by MGK, an insect control company founded in 1902. MGK began with botanical insecticide technology and later expanded into professional pest-control formulations using both botanical and conventional active ingredients. MGK has been affiliated with Sumitomo Chemical since 1989. CrossFire is registered with the U.S. Environmental Protection Agency under EPA Registration No. 1021-2776.
CrossFire is widely used in professional pest management, but the product itself is not restricted solely to licensed pest-control operators under the federal label. Availability and permitted use can still vary by state or local jurisdiction. Anyone applying CrossFire must follow the label exactly. A severe, widespread or recurring infestation may still justify professional treatment, especially when activity extends beyond one sleeping area.
CrossFire was developed specifically around the problems that make modern bed bug infestations difficult to control. It targets pyrethroid-resistant strains, kills eggs as well as mobile life stages and leaves residual activity on treated surfaces. The formula uses clothianidin and metofluthrin as insecticidal active ingredients, supported by piperonyl butoxide as a synergist. That combination gives CrossFire more than one route of attack instead of relying on a single conventional pyrethroid.
Other Pests, Other Products

Surrender Fire Ant Killer
75% acephate powder for fire ant mounds outdoors. One to two teaspoons over the mound, up to 108 mounds per can. Different pest, different chemistry, and nothing about it overlaps with an indoor bed bug program.
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Advion Cockroach Gel Bait
A gel placed in cracks and cabinet hinges for German and American roaches. Roaches eat bait, bed bugs feed only on blood, so a bait does nothing for bed bugs and a bed bug spray does little for a roach population.
Visit websiteTreat the Harborages, Not Just the Bugs You Can See
A visible bed bug is one part of an infestation. The seams, joints and protected surfaces where adults, nymphs and eggs sit out the day are where a treatment is won, and CrossFire is labeled to go directly onto most of them.
Shop CrossFire Bed Bug Concentrate